Complement in ANCA-associated vasculitis: mechanisms and implications for management

Volume: 13, Issue: 6, Pages: 359 - 367
Published: Mar 20, 2017
Abstract
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of potentially life-threatening autoimmune diseases. The main histological feature in the kidneys of patients with AAV is pauci-immune necrotizing crescentic glomerulonephritis with little immunoglobulin and complement deposition in the glomerular capillary walls. The complement system was not, therefore, initially thought to be associated with the development of...
Paper Details
Title
Complement in ANCA-associated vasculitis: mechanisms and implications for management
Published Date
Mar 20, 2017
Volume
13
Issue
6
Pages
359 - 367
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