Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: S ustained reductions in body weight, glycaemia and blood pressure over 1 year

Aims Dapagliflozin and exenatide reduce body weight by differing mechanisms. Dual therapy with these agents reduces body weight, adipose tissue volume, glycaemia and systolic blood pressure ( SBP ) over 24 weeks. Here, we examined these effects over 1 year in obese adults without diabetes. Materials and methods Obese adults without diabetes ( N = 50; aged 18‐70 years; body mass index, 30‐45 kg/m 2 ) were initially randomized to double‐blind oral...