Light-sensing via hydrogen peroxide and a peroxiredoxin

Volume: 8, Issue: 1
Published: Mar 24, 2017
Abstract
Yeast lacks dedicated photoreceptors; however, blue light still causes pronounced oscillations of the transcription factor Msn2 into and out of the nucleus. Here we show that this poorly understood phenomenon is initiated by a peroxisomal oxidase, which converts light into a hydrogen peroxide (H 2 O 2 ) signal that is sensed by the peroxiredoxin Tsa1 and transduced to thioredoxin, to counteract PKA-dependent Msn2 phosphorylation. Upon H 2 O 2 ,...
Paper Details
Title
Light-sensing via hydrogen peroxide and a peroxiredoxin
Published Date
Mar 24, 2017
Volume
8
Issue
1
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