Effect and mechanism of wedelolactone as antioxidant-coumestan on<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif" overflow="scroll"><mml:mrow><mml:msup><mml:mrow /><mml:mrow><mml:mtext /></mml:mrow></mml:msup><mml:mtext>OH</mml:mtext></mml:mrow></mml:math>-treated mesenchymal stem cells

The antioxidant properties of coumestans have been investigated previously using inappropriate methods, which has resulted in misleading and inaccurate mechanisms being reported to account for their antioxidant behavior. In this study, the phenolic coumestan wedelolactone increased the viability of OH-treated mesenchymal stem cells (MSCs) in a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl assay. Mechanistic analysis in vitro suggested that...