Original paper
Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences
Abstract
Most implementations of mass spectrometry-based proteomics involve enzymatic digestion of proteins, expanding the analysis to multiple proteolytic peptides for each protein. Currently, there is no consensus of how to summarize peptides' abundances to protein concentrations, and such efforts are complicated by the fact that error control normally is applied to the identification process, and do not directly control errors linking peptide...
Paper Details
Title
Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences
Published Date
Mar 17, 2017
Volume
16
Issue
5
Pages
936 - 948