Review paper
Potential role of CYP1B1 in the development and treatment of metabolic diseases
Abstract
Cytochrome P450 1B1 (CYP1B1), a member of CYP superfamily, is expressed in liver and extrahepatic tissues carries out the metabolism of numerous xenobiotics, including metabolic activation of polycyclic aromatic hydrocarbons. Surprisingly, CYP1B1 was also shown to be important in regulating endogenous metabolic pathways, including the metabolism of steroid hormones, fatty acids, melatonin, and vitamins. CYP1B1 and nuclear receptors including...
Paper Details
Title
Potential role of CYP1B1 in the development and treatment of metabolic diseases
Published Date
Oct 1, 2017
Journal
Volume
178
Pages
18 - 30
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