Original paper

Optogenetic control with a photocleavable protein, PhoCl

Volume: 14, Issue: 4, Pages: 391 - 394
Published: Mar 13, 2017
To expand the range of experiments that are accessible with optogenetics, we developed a photocleavable protein (PhoCl) that spontaneously dissociates into two fragments after violet-light-induced cleavage of a specific bond in the protein backbone. We demonstrated that PhoCl can be used to engineer light-activatable Cre recombinase, Gal4 transcription factor, and a viral protease that in turn was used to activate opening of the large-pore ion...
Paper Details
Optogenetic control with a photocleavable protein, PhoCl
Published Date
Mar 13, 2017
391 - 394
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.