Reconstruction of uptake patterns in PET: The influence of regularizing prior

The effects of regularizing priors on the maximum likelihood (ML) reconstruction of activity patterns in Positron Emission Tomography (PET) were assessed.Two edge-preserving priors (one originally proposed by Nuyts et al. and nowadays implemented and commercialized by General Electric Medical Systems as Q.Clear software, and a second one originally proposed by Rapisarda et al. and our group) were assessed and compared to a standard Ordered...