The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion

Volume: 12, Issue: 3, Pages: e0173486 - e0173486
Published: Mar 7, 2017
Abstract
The CXC-chemokine receptor 6 (CXCR6) is a class A GTP-binding protein-coupled receptor (GPCRs) that mediates adhesion of leukocytes by interacting with the transmembrane cell surface-expressed chemokine ligand 16 (CXCL16), and also regulates leukocyte migration by interacting with the soluble shed variant of CXCL16. In contrast to virtually all other chemokine receptors with chemotactic activity, CXCR6 carries a DRF motif instead of the typical...
Paper Details
Title
The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion
Published Date
Mar 7, 2017
Journal
Volume
12
Issue
3
Pages
e0173486 - e0173486
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