Original paper
A distinct innate lymphoid cell population regulates tumor-associated T cells
Abstract
Antitumor T cells are subject to multiple mechanisms of negative regulation. Recent findings that innate lymphoid cells (ILCs) regulate adaptive T cell responses led us to examine the regulatory potential of ILCs in the context of cancer. We identified a unique ILC population that inhibits tumor-infiltrating lymphocytes (TILs) from high-grade serous tumors, defined their suppressive capacity in vitro, and performed a comprehensive analysis of...
Paper Details
Title
A distinct innate lymphoid cell population regulates tumor-associated T cells
Published Date
Feb 6, 2017
Journal
Volume
23
Issue
3
Pages
368 - 375
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Notes
History