Serum uric acid, protein intake and mortality in hemodialysis patients

The association between serum uric acid (SUA) and mortality has been conflicting among studies using hemodialysis (HD) patients. Given the close link between purine and protein in foods, we hypothesized that normalized protein catabolic rate (nPCR), a dietary protein intake surrogate, modifies the SUA-mortality association in the HD population.We identified 4298 patients who initiated HD and had one or more SUA measurement in a contemporary...