Bone Turnover Markers in the Diagnosis and Monitoring of Metabolic Bone Disease

Disorders of bone metabolism, most notably osteoporosis, are highly prevalent and predispose to fractures, causing high patient morbidity and mortality. Diagnosis and monitoring of bone metabolic defects can present a major challenge as these disorders are largely asymptomatic and radiographic measures of bone mass respond slowly to changes in bone physiology.Bone turnover markers (BTMs) are a series of protein or protein derivative biomarkers...