Regulated complex assembly safeguards the fidelity ofSleeping Beautytransposition

Volume: 45, Issue: 1, Pages: 311 - 326
Published: Dec 1, 2016
Abstract
The functional relevance of the inverted repeat structure (IR/DR) in a subgroup of the Tc1/mariner superfamily of transposons has been enigmatic. In contrast to mariner transposition, where a topological filter suppresses single-ended reactions, the IR/DR orchestrates a regulatory mechanism to enforce synapsis of the transposon ends before cleavage by the transposase occurs. This ordered assembly process shepherds primary transposase binding to...
Paper Details
Title
Regulated complex assembly safeguards the fidelity ofSleeping Beautytransposition
Published Date
Dec 1, 2016
Volume
45
Issue
1
Pages
311 - 326
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.