Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes
Abstract
Netrins, a family of laminin-related molecules, have been proposed to act as guidance cues either during nervous system development or the establishment of the vascular system. This was clearly demonstrated for netrin-1 via its interaction with the receptors DCC and UNC5s. However, mainly based on shared homologies with netrin-1, netrin-4 was also proposed to play a role in neuronal outgrowth and developmental/pathological angiogenesis via...
Paper Details
Title
Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes
Published Date
Nov 30, 2016
Journal
Volume
7
Issue
1
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