Original paper
Molecular Markers of Radiation Induced Attenuation in Intrahepatic Plasmodium falciparum Parasites
Abstract
Experimental immunization with radiation attenuated sporozoites (RAS) and genetically attenuated sporozoites has proved to be a promising approach for malaria vaccine development. However, parasite biomarkers of growth attenuation and enhanced immune protection in response to radiation remain poorly understood. Here, we report on the effect of an attenuating dose of γ-irradiation (15 krad) on the Plasmodium falciparum sporozoite (PfSPZ)...
Paper Details
Title
Molecular Markers of Radiation Induced Attenuation in Intrahepatic Plasmodium falciparum Parasites
Published Date
Dec 2, 2016
Journal
Volume
11
Issue
12
Pages
e0166814 - e0166814
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Notes
History