Original paper
Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
Abstract
In this cross-sectional study, we aimed to evaluate brain structural abnormalities in relation to glial activation in the same cohort of participants.Ten individuals with amyotrophic lateral sclerosis (ALS) and 10 matched healthy controls underwent brain imaging using integrated MR/PET and the radioligand [11C]-PBR28. Diagnosis history and clinical assessments including Upper Motor Neuron Burden Scale (UMNB) were obtained from patients with ALS....
Paper Details
Title
Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
Published Date
Nov 12, 2016
Journal
Volume
87
Issue
24
Pages
2554 - 2561