Early start of DOAC after ischemic stroke

Objective:

In patients with recent acute ischemic stroke (AIS) and atrial fibrillation, we assessed the starting time of direct, non–vitamin K antagonist oral anticoagulants (DOACs) for secondary prevention, the rate of intracranial hemorrhage (ICH), and recurrent ischemic events during follow-up.

Methods:

We included consecutive patients with nonvalvular atrial fibrillation admitted to our hospital for AIS or TIA (index event)...