Sevoflurane for Sedation in Acute Respiratory Distress Syndrome. A Randomized Controlled Pilot Study

Sevoflurane improves gas exchange, and reduces alveolar edema and inflammation in preclinical studies of lung injury, but its therapeutic effects have never been investigated in acute respiratory distress syndrome (ARDS).To assess whether sevoflurane would improve gas exchange and inflammation in ARDS.We did a parallel, open-label single-center randomized controlled trial at three intensive care units from a French university hospital between...