Excretions/secretions from medicinal larvae (Lucilia sericata) inhibit complement activation by two mechanisms

Larvae of the blowfly Lucilia sericata facilitate wound healing by removing dead tissue and biofilms from non‐healing and necrotic wounds. Another beneficial action of larvae and their excretions/secretions (ES) is down‐regulation of excessive inflammation. As prolonged complement activation is key to excessive inflammation, the aim of this study was to elucidate the mechanisms underlying the anti‐complement activities of ES. Results revealed...