Regulatory circuits of T cell function in cancer

Volume: 16, Issue: 10, Pages: 599 - 611
Published: Aug 16, 2016
Abstract
In this Review, the authors summarize the features and the molecular drivers of T cell dysfunction in cancer and compare these with dysfunctional T cells in chronic viral infection. The metabolic competition in the tumour microenvironment is also discussed. Understanding antitumour T cell responses has important implications for cancer...
Paper Details
Title
Regulatory circuits of T cell function in cancer
Published Date
Aug 16, 2016
Volume
16
Issue
10
Pages
599 - 611
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