Assessment of Minimum 124I Activity Required in Uptake Measurements Before Radioiodine Therapy for Benign Thyroid Diseases

This study aimed to assess a hypothetical minimum administered activity of ¹²⁴I required to achieve comparability between pretherapeutic radioiodine uptake (RAIU) measurements by ¹²⁴I PET/CT and by ¹³¹I RAIU probe, the clinical standard. In addition, the impact of different reconstruction algorithms on ¹²⁴I RAIU and the evaluation of pixel noise as a parameter for image quality were investigated....