Original paper
Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases
Abstract
For the majority of congenital heart diseases (CHDs), the full complexity of the causative molecular network, which is driven by genetic, epigenetic, and environmental factors, is yet to be elucidated. Epigenetic alterations are suggested to play a pivotal role in modulating the phenotypic expression of CHDs and their clinical course during life. Candidate approaches implied that DNA methylation might have a developmental role in CHD and...
Paper Details
Title
Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases
Published Date
Aug 5, 2016
Journal
Volume
112
Issue
1
Pages
464 - 477