A mouse retinal explant model for use in studying neuroprotection in glaucoma
Abstract
The study aims to validate mouse retinal explants for use as an efficient tool to investigate neuroprotective therapies for treatment in diseases such as glaucoma. Eyes from C57BL/6 mice were enucleated immediately post-mortem to make two retinal explants per eye. Explants were cultured at an air/medium interface on membrane inserts for 7 days ex-vivo. Explants were treated either with Z-VAD-FMK (a pan-caspase inhibitor; 100 μM) or vehicle....
Paper Details
Title
A mouse retinal explant model for use in studying neuroprotection in glaucoma
Published Date
Oct 1, 2016
Journal
Volume
151
Pages
38 - 44
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