Original paper
Efficient production and enhanced tumor delivery of engineered extracellular vesicles
Abstract
Extracellular vesicles (EV), including exosomes and microvesicles, are nano-sized intercellular communication vehicles that participate in a multitude of physiological processes. Due to their biological properties, they are also promising candidates for the systemic delivery of therapeutic compounds, such as cytokines, chemotherapeutic drugs, siRNAs and viral vectors. However, low EV production yield and rapid clearance of administered EV by...
Paper Details
Title
Efficient production and enhanced tumor delivery of engineered extracellular vesicles
Published Date
Oct 1, 2016
Journal
Volume
105
Pages
195 - 205
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Notes
History