LRP1 expression in microglia is protective during CNS autoimmunity

Volume: 4, Issue: 1
Published: Jul 11, 2016
Abstract
Multiple sclerosis is a devastating neurological disorder characterized by the autoimmune destruction of the central nervous system myelin. While T cells are known orchestrators of the immune response leading to MS pathology, the precise contribution of CNS resident and peripheral infiltrating myeloid cells is less well described. Here, we explore the myeloid cell function of Low-density lipoprotein receptor-related protein-1 (LRP1), a scavenger...
Paper Details
Title
LRP1 expression in microglia is protective during CNS autoimmunity
Published Date
Jul 11, 2016
Volume
4
Issue
1
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