Original paper

RNAi delivery by exosome-mimetic nanovesicles – Implications for targeting c-Myc in cancer

Volume: 102, Pages: 231 - 238
Published: Sep 1, 2016
Abstract
To develop RNA-based therapeutics, it is crucial to create delivery vectors that transport the RNA molecule into the cell cytoplasm. Naturally released exosomes vesicles (also called “Extracellular Vesicles”) have been proposed as possible RNAi carriers, but their yield is relatively small in any cell culture system. We have previously generated exosome-mimetic nanovesicles (NV) by serial extrusions of cells through nano-sized filters, which...
Paper Details
Title
RNAi delivery by exosome-mimetic nanovesicles – Implications for targeting c-Myc in cancer
Published Date
Sep 1, 2016
Volume
102
Pages
231 - 238
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