Therapeutic Advances in Localized Pancreatic Cancer

Importance

It is estimated that pancreatic cancer (PC) will become the second leading cause of cancer-related death in the United States by 2030.

Observations

Clinical and preclinical data support the understanding that PC metastases occur early in the pathogenesis of this disease, even before the primary tumor can be detected. This has important implications for the clinical management of patients with localized PC, as surgery...