Prognostic potential of theMDM2309T>G polymorphism in stage I lung adenocarcinoma

Volume: 5, Issue: 8, Pages: 1791 - 1801
Published: May 26, 2016
Abstract
The MDM2 protein plays an important role in the regulation of cell proliferation and apoptosis via ubiquitination and proteasome-mediated degradation of p53. The genetic polymorphism rs2279744 (c.309T>G) of the MDM2 gene is reportedly associated with susceptibility and/or prognosis in various cancers. In this study, we investigated the risk factors for worse survival in patients with lung adenocarcinoma (AC). We examined the association between...
Paper Details
Title
Prognostic potential of theMDM2309T>G polymorphism in stage I lung adenocarcinoma
Published Date
May 26, 2016
Volume
5
Issue
8
Pages
1791 - 1801
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