Prenatal Nicotine Exposure and Risk of Schizophrenia Among Offspring in a National Birth Cohort

Cigarette smoking during pregnancy is a major public health problem leading to adverse health outcomes and neurodevelopmental abnormalities among offspring. Its prevalence in the United States and Europe is 12%-25%. This study examined the relationship between prenatal nicotine exposure (cotinine level) in archived maternal sera and schizophrenia in offspring from a national birth cohort.The authors conducted a population-based nested...