Expression and clinical significance of CD1a+ dendritic cells in glottic squamous cell carcinoma

BACKGROUND & OBJECTIVE Dendritic cells (DCs) are the most important antigen-presenting cells. CD1a, a marker of immature DCs, plays a role in tumorigenesis. This study was designed to explore the correlation of CD1a(+) DCs to pathologic degree, T stage, local recurrence, and prognosis of glottic squamous cell carcinoma. METHODS Clinical and follow-up data of 111 patients with glottic squamous cell carcinoma were analyzed retrospectively. The...