The role of mitochondrial sirtuins in health and disease

Volume: 100, Pages: 164 - 174
Published: Nov 1, 2016
Abstract
Mitochondria play a critical role in energy production, cell signalling and cell survival. Defects in mitochondrial function contribute to the ageing process and ageing-related disorders such as metabolic disease, cancer, and neurodegeneration. The sirtuin family of deacylase enzymes have a variety of subcellular localisations and have been found to remove a growing list of post-translational acyl modifications from target proteins. SIRT3,...
Paper Details
Title
The role of mitochondrial sirtuins in health and disease
Published Date
Nov 1, 2016
Volume
100
Pages
164 - 174
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