Clinical score to predict the risk of bile leakage after liver resection.

Published on May 6, 2016in BMC Surgery2.102
· DOI :10.1186/S12893-016-0147-0
Takahiro Kajiwara3
Estimated H-index: 3
(Nihon University),
Yutaka Midorikawa31
Estimated H-index: 31
(Nihon University)
+ 5 AuthorsTadatoshi Takayama92
Estimated H-index: 92
(Nihon University)
Sources
Abstract
Background In liver resection, bile leakage remains the most common cause of operative morbidity. In order to predict the risk of this complication on the basis of various factors, we developed a clinical score system to predict the potential risk of bile leakage after liver resection.
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References29
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#1Shintaro Yamazaki (Nihon University)H-Index: 17
#2Tadatoshi Takayama (Nihon University)H-Index: 92
Last. Tokio Higaki (Nihon University)H-Index: 12
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Background: Abdominal drains have been placed prophylactically and removed in liver resection without robust evidence. The present study was designed to establish the optimal time for removal of such drains. Methods: Data on abdominal prophylactic drains were analysed in a consecutive series of patients who underwent liver resection for malignancy between 2006 and 2009. Bilirubin levels in drain fluid were measured and bacteriological cultures were taken on days 1, 3, 5 and 7 after surgery. Drai...
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#1Hiromichi Ishii (Kyoto Prefectural University of Medicine)H-Index: 7
#2Toshiya OchiaiH-Index: 25
Last. Eigo OtsujiH-Index: 59
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Background/Aims: Bile leakage frequently causes major complications after hepatic resection. We investigated perioperative risk factors and management of postoperative bile leakage
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#1Moritz Koch (Heidelberg University)H-Index: 53
#2O. James Garden (Edin.: University of Edinburgh)H-Index: 51
Last. Jürgen Weitz (Heidelberg University)H-Index: 76
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Background Despite the potentially severe impact of bile leakage on patients’ perioperative and long-term outcome, a commonly used definition of this complication after hepatobiliary and pancreatic operations has not yet been established. The aim of the present article is to propose a uniform definition and severity grading of bile leakage after hepatobiliary and pancreatic operative therapy. Methods An international study group of hepatobiliary and pancreatic surgeons was convened. A consensus ...
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#1Ryuji Yoshioka (JFCR: Japanese Foundation for Cancer Research)H-Index: 11
#2Akio Saiura (JFCR: Japanese Foundation for Cancer Research)H-Index: 38
Last. Junji Yamamoto (National Defense Medical College)H-Index: 52
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Background Bile leakage is the most common complication after hepatectomy and its incidence is not declining. The aim of the present study was to identify predictive factors for bile leakage.
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Surgery is the most important therapeutic approach for patients with hepatocellular carcinoma. We have reviewed patients’ survival after resection for hepatocellular carcinoma in 17 series since 2000, each including more than 100 patients. Median survival rates were 80% (range 63 –97%) at 1 year, 70% (34 –78%) at 3 years and 50% (17 –6 9%) at 5 years. Such wide ranges of survival rates are attributed mainly to differences in the hepatocellular carcinoma stage among studies, but the survival rate...
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Background The value of prophylactic abdominal drainage in patients undergoing hepatectomy is controversial. We carried out a retrospective study to clarify the value of this procedure.
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#1Luca ViganòH-Index: 37
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Last. Lorenzo CapussottiH-Index: 67
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Abstract Background Bile leakage after hepatectomy usually has spontaneous healing, but some patients require interventional procedures. To identify early predictive factors of conservative management failure. Methods This study focused on patients with bile leak after hepatectomy without extrahepatic biliary resection from 1996 through 2006. Results Bile leakage occurred in 34 of 593 patients (5.7%). Conservative management was successful in 26 patients (76.5%). At univariate analysis overall a...
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#2James S. Michaelson (Harvard University)H-Index: 42
Last. Kenneth K. Tanabe (Harvard University)H-Index: 83
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Background Liver resection is performed with increasing frequency. Nearly all of the published information on operative mortality and morbidity rates associated with liver resection is derived from studies that rely on retrospective data collection from single centers. The goal of this study is to use audited multiinstitutional data from the private sector of the Patient Safety in Surgery Study to characterize complications after liver resection and to identify variables that are associated with...
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#2Alessandro Cojutti (University of Udine)H-Index: 8
Last. Alessandro Uzzau (University of Udine)H-Index: 15
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Introduction Notwithstanding technical advances and high experience of liver resection of specialized centers, the rate of complications after surgical resection could be high. In this study, we analyzed causes and foreseeable risk factors linked to postoperative morbidity on the ground of data derived from a single center surgical population.
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#1Lorenzo CapussottiH-Index: 67
#2Alessandro FerreroH-Index: 33
Last. Roberto PolastriH-Index: 17
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Hypothesis The knowledge of risk factors for bile leakage after liver resection could reduce its incidence. Design Retrospective study. Setting Tertiary care referral center. Patients The study included 610 patients who underwent liver resection from January 1, 1989, through January 31, 2003. Interventions Liver resections without biliary anastomoses. Main Outcome Measures Bile leakage incidence and its correlation to preoperative and intraoperative patient characteristics. Results Postoperative...
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Last. Yuko Kitagawa (Keio: Keio University)H-Index: 77
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Despite the increasing number of laparoscopic liver resection (LLR) procedures, postoperative bile leakage (POBL) remains a major complication. We occasionally experienced intraoperative bile leakage (IOBL) during LLR and managed it within the restrictions of laparoscopic surgery. However, there have been no reports about IOBL in LLR. We therefore investigated the impact of IOBL on postoperative outcomes and its predictive factors. We reviewed 137 patients who underwent LLR from April 2016 to Ma...
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Background. Laparoscopic liver resection (LLR) has emerged as a considerable alternative to conventional liver surgery. However, the increasing complexity of liver resection raises the incidence of postoperative complications. The aim of this study was to identify risk factors for postoperative morbidity in a monocentric cohort of patients undergoing LLR. Methods. All consecutive patients who underwent LLR between 2015 and 2019 at our institution were analyzed for associations between complicati...
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#1Zhobin Moghadamyeghaneh (SUNY: State University of New York System)H-Index: 17
#2Alec F Krosser (SUNY: State University of New York System)
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We aimed to investigate contemporary management and outcomes of bile leakage in patients who underwent hepatectomy with hepaticojejunostomy for liver malignancy. The NSQIP database was used to study clinical data of patients who underwent a hepatectomy with hepaticojejunostomy for a primary hepatobiliary cancer and developed bile leakage between 1/2014 and 12/2017. Multivariate regression analysis was performed to investigate outcomes. Five hundred patients underwent a hepatectomy with hepaticoj...
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#1Ling Tan (Chengdu Medical College)H-Index: 1
#2Fei Liu (Chengdu Medical College)
Last. Jiang-Wei Xiao (Chengdu Medical College)H-Index: 3
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Background and Aim The risk factors for bile leakage after hepatectomy without biliary reconstruction are controversial. This study investigated the risk factors for bile leakage after hepatectomy without biliary reconstruction. Methods We searched databases (Embase (Ovid), Medline (Ovid), PubMed, Cochrane Library, and Web of Science) for articles published between January 1, 2000, and May 1, 2021, to evaluate the risk factors for bile leakage after hepatectomy without biliary reconstruction. Re...
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#1Alison Smith (Tulane University)H-Index: 8
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Introduction The reported rate of postoperative bile leak is variable between 3 and 33%. Recent data would suggest a minimally invasive approach to liver surgery has decreased this incidence.
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#1Jing Wang (HUST: Huazhong University of Science and Technology)H-Index: 246
Summary Background The impact of bile leakage (BL) on the long-term prognosis in patients with primary liver cancers after hepatectomy remains unclear. Methods One thousand nine hundred and seventy-one consecutive patients with primary liver cancers who underwent curative hepatectomy were enrolled. 75 patients encountered BL, including 34 long-time BL (LTBL) and 41 short-time BL (STBL) according to 4-weeks demarcation. Variables associated with BL were identified using multiple logistic regressi...
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#1Tamotsu KurokiH-Index: 10
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