Original paper
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs
Abstract
Growth inhibition metrics allow for robust measurement of drug efficacy independent of variables such as cell growth rate, seeding density, and growth medium; they are a practical alternative to metrics such as IC50 and offer enhanced reproducibility. Drug sensitivity and resistance are conventionally quantified by IC50 or Emax values, but these metrics are highly sensitive to the number of divisions taking place over the course of a response...
Paper Details
Title
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs
Published Date
May 2, 2016
Journal
Volume
13
Issue
6
Pages
521 - 527
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Notes
History