Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.
Abstract
The development of immune-dependent drug hypersensitivity reactions (IDHR) is likely to involve activation of the innate immune system to stimulate neo-antigen specific T-cells. Previously it has been shown that, upon oral exposure to several drugs with immune-adjuvant capacity, mice developed T-cell-dependent responses to TNP-OVA. These results were indicative of the adjuvant potential of these drugs. The present study set out to evaluate the...
Paper Details
Title
Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen.
Published Date
Apr 4, 2016
Journal
Volume
13
Issue
4
Pages
535 - 547
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Notes
History