Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors

Epidemiological findings suggest a relationship between multiple sclerosis (MS) and cardiovascular disease (CVD) risk factors, although the nature of this relationship is not well understood.We used genome-wide association study (GWAS) data to identify shared genetic factors (pleiotropy) between MS and CVD risk factors.Using summary statistics from a large, recent GWAS (total n > 250,000 individuals), we investigated overlap in single nucleotide...