Original paper
Influence of Biophysical Parameters on Maintaining the Mesenchymal Stem Cell Phenotype
Volume: 1, Issue: 4, Pages: 218 - 226
Published: Mar 6, 2015
Abstract
The maintenance of the mesenchymal stem cell (MSC) phenotype in vivo is influenced by the precise orchestration of biochemical and biophysical signals in the stem cell “niche”. However, when MSCs are removed from the body and expanded in vitro, there is a loss of multipotency. Here, we employ micropatterned hydrogels to explore how biophysical cues influence the retention of MSC multipotency marker expression. At the single-cell level, soft...
Paper Details
Title
Influence of Biophysical Parameters on Maintaining the Mesenchymal Stem Cell Phenotype
Published Date
Mar 6, 2015
Volume
1
Issue
4
Pages
218 - 226
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Notes
History