Original paper

Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics

Volume: 6, Issue: 1
Published: Feb 22, 2016
Abstract
We present a new, rapid method for producing blood platelets in vitro from cultured megakaryocytes based on a microfluidic device. This device consists in a wide array of VWF-coated micropillars. Such pillars act as anchors on megakaryocytes, allowing them to remain trapped in the device and subjected to hydrodynamic shear. The combined effect of anchoring and shear induces the elongation of megakaryocytes and finally their rupture into...
Paper Details
Title
Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics
Published Date
Feb 22, 2016
Volume
6
Issue
1
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.