Original paper
Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
Abstract
Retinal neovascularization, as occurs in age-related macular degeneration, may result from an increase in VEGFA levels due to dysregulated lipid and glucose metabolism within photoreceptors. Tissues with high metabolic rates often use lipids, as well as glucose, for energy, conferring a survival advantage during feast and famine1. Current dogma suggests that high-energy–consuming photoreceptors depend on glucose2,3. Here we show that the retina...
Paper Details
Title
Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
Published Date
Mar 14, 2016
Journal
Volume
22
Issue
4
Pages
439 - 445
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Notes
History