Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer

Volume: 11, Issue: 10_Supplement, Pages: B046 - B046
Published: Oct 1, 2013
Abstract
Background: Integrin αvβ6 promotes migration, invasion and survival of cancer cells, however, the relevance and role of αvβ6 has yet to be elucidated in breast cancer. Methods: Protein expression of integrin subunit beta6 (β6) was measured in over 2000 breast cancers by immunohistochemistry and ITGB6 mRNA expression measured in the METABRIC dataset. Overall survival was assessed using Kaplan-Meier curves and bioinformatics statistical analyses...
Paper Details
Title
Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer
Published Date
Oct 1, 2013
Volume
11
Issue
10_Supplement
Pages
B046 - B046
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