Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
Abstract
The epithelial to mesenchymal transition (EMT) is a biological process in which a non-motile epithelial cell changes to a mesenchymal phenotype with invasive capacities. This phenomenon has been well documented in multiple biological processes including embryogenesis, fibrosis, tumor progression and metastasis. The hallmark of EMT is the loss of epithelial surface markers, most notably E-cadherin, and the acquisition of mesenchymal markers...
Paper Details
Title
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
Published Date
Feb 24, 2016
Journal
Volume
15
Issue
1
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