Review paper
Rabbit antithymocyte globulin and donor-specific antibodies in kidney transplantation — A review
Abstract
The mode of action of rabbit antithymocyte globulin (rATG) includes preferential inhibition of pre-existing donor-reactive memory T-cell reconstitution and possibly apoptosis of plasma cells, the source of donor specific antibodies (DSAs). In kidney transplant patients with low-strength preformed DSAs, non-comparative data have shown a low incidence of antibody-mediated rejection (ABMR) and graft survival using rATG even without desensitization...
Paper Details
Title
Rabbit antithymocyte globulin and donor-specific antibodies in kidney transplantation — A review
Published Date
Apr 1, 2016
Journal
Volume
30
Issue
2
Pages
85 - 91
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Notes
History