Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway
Abstract
The present study was conducted to investigate the protective effect of betulin, a triterpene from the bark of Betula platyphylla Suk, against ethanol-induced alcoholic liver injury and its possible underlying mechanisms. In vitro, human hepatic stellate cell line, LX-2 cells were treated with betulin (6.25, 12.5 and 25 μM) prior to ethanol (50mM) for 24h. Cell viability was analyzed by methyl thiazolyl tetrazolium assay, protein expressions...
Paper Details
Title
Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway
Published Date
Mar 1, 2016
Journal
Volume
105
Pages
1 - 12
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