Review paper
Immunotoxins: a clinical review of their use in the treatment of malignancies.
Abstract
Immunotoxins are a new class of antitumor agents consisting of tumor-selective ligands (generally monoclonal antibodies [MoAbs]) linked to highly toxic protein molecules that have been modified to remove their normal tissue-binding domains. These immuno-conjugates combine the potency of the parent toxin with the specificity of the attached ligand. Toxins used in the construction of immunotoxins belong to a group of peptides that catalytically...
Paper Details
Title
Immunotoxins: a clinical review of their use in the treatment of malignancies.
Published Date
Dec 1, 1989
Journal
Volume
7
Issue
12
Pages
1932 - 1942
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Notes
History