Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

Volume: 240, Pages: 332 - 348
Published: Oct 1, 2016
Abstract
30-99% of administered nanoparticles will accumulate and sequester in the liver after administration into the body. This results in reduced delivery to the targeted diseased tissue and potentially leads to increased toxicity at the hepatic cellular level. This review article focuses on the inter- and intra-cellular interaction between nanoparticles and hepatic cells, the elimination mechanism of nanoparticles through the hepatobiliary system,...
Paper Details
Title
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
Published Date
Oct 1, 2016
Volume
240
Pages
332 - 348
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