Review paper
DNA damage and the balance between survival and death in cancer biology
Abstract
DNA is vulnerable to damage resulting from endogenous metabolites, environmental and dietary carcinogens, some anti-inflammatory drugs, and genotoxic cancer therapeutics. Cells respond to DNA damage by activating complex signalling networks that decide cell fate, promoting not only DNA repair and survival but also cell death. The decision between cell survival and death following DNA damage rests on factors that are involved in DNA damage...
Paper Details
Title
DNA damage and the balance between survival and death in cancer biology
Published Date
Dec 18, 2015
Journal
Volume
16
Issue
1
Pages
20 - 33
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