Review paper
Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function
Abstract
There is increasing evidence that sensory nerves may participate in cutaneous inflammatory responses by the release of neuropeptides such as substance P (SP). We examined the direct effect of SP on human dermal microvascular endothelial cell (HDMEC) intercellular adhesion molecule 1 (ICAM-1) expression and function. Our results indicated that, although cultured HDMEC expressed mRNA for neurokinin receptors 1, 2, and 3 (NK-1R, NK-2R, and NK-3R),...
Paper Details
Title
Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function
Published Date
Dec 1, 1998
Journal
Volume
275
Issue
6
Pages
C1580 - C1590
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Notes
History