Temporal Trends in the Use of Anticoagulants Among Older Adults With Atrial Fibrillation

Several recent randomized clinical trials have demonstrated that warfarin sodium treatment, and to a lesser extent aspirin, reduces risk of stroke and death compared with placebo in persons with atrial fibrillation. Insufficient documentation exists on the extent to which the use of these therapies following trial publications has continued to increase in the elderly with atrial fibrillation.We used data from the Cardiovascular Health Study, a...