Original paper
The datA locus predominantly contributes to the initiator titration mechanism in the control of replication initiation in Escherichia coli
Abstract
Replication of the Escherichia coli chromosome is initiated synchronously from all origins (oriC) present in a cell at a fixed time in the cell cycle under given steady state culture conditions. A mechanism to ensure the cyclic initiation events operates through the chromosomal site, datA, which titrates exceptionally large amounts of the bacterial initiator protein, DnaA, to prevent overinitiation. Deletion of the datA locus results in extra...
Paper Details
Title
The datA locus predominantly contributes to the initiator titration mechanism in the control of replication initiation in Escherichia coli
Published Date
May 23, 2002
Journal
Volume
44
Issue
5
Pages
1367 - 1375
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Notes
History