Therapeutic value of melatonin post-treatment on CCl4-induced fibrotic rat liver
Volume: 94, Issue: 2, Pages: 119 - 130
Published: Feb 1, 2016
Abstract
Melatonin is known for being beneficial in targeting liver diseases. This study aimed to investigate whether melatonin post-treatment is capable of rat carbon tetrachloride (CCl4)-induced liver fibrosis reduction. Thirty-two male Sprague-Dawley rats were divided into 4 groups: normal; fibrosis with CCl4 injection (1 mL/kg) twice weekly for 8 weeks; phosphate-buffered saline (PBS); and melatonin (20 mg/kg) for a further 4 weeks on cessation of...
Paper Details
Title
Therapeutic value of melatonin post-treatment on CCl4-induced fibrotic rat liver
Published Date
Feb 1, 2016
Volume
94
Issue
2
Pages
119 - 130
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