Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2Close KATPChannels and Induce Insulin Secretion
Volume: 310, Issue: 3, Pages: 1273 - 1280
Published: Jun 16, 2004
Abstract
It is known that peroxisome proliferator-activated receptor-γ (PPAR-γ) ligands stimulate acute-phase insulin secretion with a rapid Ca2+ influx into pancreatic β-cells, but the precise mechanisms are not clear. The effects of PPAR-α ligands on pancreatic β-cells also remain unclear. We investigated the effects of PPAR-α ligands (fenofibrate and fenofibric acid), a PPAR-γ ligand (troglitazone), and an endogenous ligand of PPAR-γ...
Paper Details
Title
Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2Close KATPChannels and Induce Insulin Secretion
Published Date
Jun 16, 2004
Volume
310
Issue
3
Pages
1273 - 1280
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